The Card-EV Project, led by the Jagiellonian University in Kraków in partnership with the Institute of Human Genetics of the Polish Academy of Sciences, aims to develop a new generation of advanced medicinal products based on extracellular vesicles (EVs) derived from stem cells. These novel therapeutic solutions are being developed specifically for the treatment of cardiovascular diseases (CVDs)—one of the leading causes of death globally and the primary cause of mortality in Poland (accounting for approximately 46% of all deaths according to Statistics Poland).
The project has been awarded funding of PLN 8.3 million under the TEAM-NET FENG programme – an initiative of the Foundation for Polish Science (FNP) supported by the European Funds for a Modern Economy (FENG).
This interdisciplinary research initiative has the potential to generate significant impact:
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Social: The development of EV-based therapies may revolutionize the treatment of cardiovascular diseases, offering safer and more effective therapeutic options.
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Economic: The global cell and gene therapy market, valued at over $30 billion in 2024, is projected to exceed $190 billion by 2033, indicating a high commercialization potential for innovative biomedical technologies.
The scientific leaders of the project are:
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Prof. Ewa Zuba-Surma, PhD, DSc – Jagiellonian University
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Prof. Natalia Rozwadowska, PhD, DSc – Institute of Human Genetics, PAS
“The selected projects are based on excellent quality initial results and well-planned collaboration between research teams. Thanks to these features, the awarded projects have a chance to result in breakthrough solutions on the market,”
— Dr. Radosław Kwapiszewski, Eng., Deputy Director for Programme Activities, Foundation for Polish Science (FNP)
The TEAM-NET FENG programme aims to stimulate collaboration among top-tier research institutions in Poland, supporting strategic research and development efforts in areas such as health, environment, and Industry 4.0, with a strong emphasis on the commercialization of scientific outcomes.
Out of 81 institutions participating in the 1/2024 call, only three projects were selected for funding, with a combined budget of nearly PLN 33 million.